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Therapies & Interventions

iNAP Therapy

A negative pressure oral appliance therapy that uses suction to stabilize the soft palate and tongue during sleep.

January 2025Reviewed by: Sleep Care Directory Medical Team
OverviewBenefitsSide EffectsVariationsTips
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What is iNAP Therapy?

iNAP (intra-oral negative airway pressure) is an alternative treatment for obstructive sleep apnea that uses negative pressure to stabilize soft tissues during sleep. The system consists of a soft silicone mouthpiece connected to a small vacuum unit. Gentle suction draws the soft palate downward and the tongue forward, preventing the collapse that causes obstruction. iNAP offers another option for patients seeking alternatives to CPAP or traditional oral appliances.

How It Works

The iNAP mouthpiece creates a chamber around the tongue when placed in the mouth. A tube connects to a battery-powered vacuum unit that generates continuous gentle negative pressure. This suction stabilizes the soft palate in a downward position and holds the tongue forward without requiring jaw advancement. The open design allows normal breathing through both nose and mouth.

Who Is It For?

iNAP may be considered for patients with mild to moderate obstructive sleep apnea who prefer an alternative to CPAP or don't want the jaw advancement of traditional oral appliances. It may be helpful for patients who have TMJ problems that preclude mandibular advancement devices.

Benefits

No Jaw Advancement Required

Unlike mandibular advancement devices, iNAP doesn't reposition the jaw, avoiding TMJ stress and bite changes.

Soft, Flexible Design

The silicone mouthpiece is softer than hard acrylic oral appliances, potentially improving comfort.

Alternative Mechanism

For patients who've failed other treatments, the unique negative pressure approach may succeed where others haven't.

Allows Mouth Breathing

The open design permits breathing through the mouth, unlike nasal CPAP.

Side Effects & Considerations

Most side effects are minor and can often be resolved with simple adjustments.

Learning Curve

Using the device correctly takes practice. Initial nights may be challenging.

Dry Mouth

The suction and airflow may cause oral dryness in some users.

Noise

The vacuum unit, while quiet, produces some sound that may bother light sleepers.

Less Clinical Data

Compared to CPAP and traditional oral appliances, less independent clinical research exists on iNAP.

Fitting and Adjustment

Proper fit of the mouthpiece is important for effectiveness and comfort.

Variations & Types

iNAP Sleep Therapy System

The complete system including mouthpiece, tubing, and vacuum unit.

Different Mouthpiece Sizes

Various mouthpiece sizes accommodate different mouth and tongue sizes.

Tips for Success

Practice Before Sleep

Get comfortable with the device while awake before attempting to sleep with it.

Ensure Proper Fit

Work with your provider to ensure the mouthpiece is the right size and positioned correctly.

Maintain Nasal Breathing When Possible

While mouth breathing is possible, nasal breathing may enhance effectiveness.

Keep Equipment Clean

Regularly clean the mouthpiece and check the vacuum unit to maintain hygiene and function.

Monitor Effectiveness

Track symptoms and consider follow-up testing to ensure the device is adequately controlling your OSA.

Additional Resources

iNAP Sleep

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Search our directory for sleep clinics that offer inap therapy.

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Conditions Treated

  • Obstructive Sleep Apnea
  • Snoring

Related Treatments

  • Oral Appliance Therapy
  • CPAP Therapy
  • Sleep Apnea Treatment
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